简介:
臧玉峰,医学博士,教授,博士生导师。杭州师范大学心理科学研究院执行院长、浙江省认知障碍评估技术重点实验室执行主任。1984于年河北医学院获医学学士学位、1991年于天津医学院获神经外科学硕士学位(师从薛庆澄教授)、2002年于北京大学精神卫生研究所获精神病学博士学位(师从王玉凤教授)。曾经从事神经外科临床工作十余年,并先后中科院模式识别国家重点实验室、北师大认知神经科学与学习国家重点实验室、杭师大认知与脑疾病研究中心从事科研工作。近年来一直从事静息态功能磁共振影像的计算方法学及其在认知与脑疾病的应用的研究。提出“局一致性”(Zang et al., 2004. NeuroImage. 被引用1446次,谷歌学术,下同)和“低频振幅”(Zang et al., 2007. Brain Dev. 被引用1573)、比值低频振幅(Zou et al., 2008. J Neurosci Methods. 被引用933次)等方法。带领研究团队开发了REST(Song et al., 2011. PLOS One.被引用1468次)、DPARSF(Yan & Zang, Front Sys Neurosci.被引用2027次)、REST-GCA、RESTplus等软件。合作领导多中心合作静息态功能磁共振研究(Yan et al., 2019, PNAS.被引用22次)。将静息态功能磁共振应用于自动记忆巩固研究(Wang et al., 2012, NeurReport; 2012, PLOS One)。合作发表英语论文100多篇,Google Scholar数据库引用2万多次(h 指数69)。2014到2019年连续6年入选Elsevier中国高被引学者(神经科学),2017-2018年连续2年入选Clarivate Analytics全球高被引学者(神经与行为科学)。
课题组招生意向:
课题组从事的研究包括但不限于:(1)注意及ADHD相关认知机制、学校心理学、临床认知神经科学、ADHD治疗等研究;(2)磁共振引导的精准定位经颅磁刺激对认知与脑疾病的调控;(3)静息态功能磁共振相关的方法学研究。
希望不管是学术硕士还是专业硕士,通过三年的培养,不管是将来读博还是直接工作,既有扎实的理论基础、又有非常强的实践能力。
联系方式:
E-mail:zangyufengrest@foxmail.com; zangyf@gmail.com; zangyf@hznu.edu.cn
个人履历
学习经历:
1979.9–1984.8:河北医学院医疗系,学士
1988.8–1991.9:天津医学院神经病学专业,硕士
1998.8–2001.7:北京大学精神卫生研究所,博士(2002年获博士学位)
工作经历:
1984.8–1988.8: 河北医学院二院神经外科,住院医师
1991.9–1994.12:河北医学院二院神经外科,主治医师
1995.1–1998.8: 石家庄市脑系科医院神经外科,科主任,主治医师(-1997)、副主任医师(1997-1998)
2001.7–2002.7:中科院心理所,访问研究
2002.7–2004.6:中科院自动化所,博士后
2004.7–2005.7:中科院自动化所模式识别国家重点实验室,副研究员
2005.8–2011.2:北京师范大学认知神经科学与学习国家重点实验室,研究员
2011.3–至今: 杭州师范大学心理科学研究院,教授
科学研究
在科研项目:
1.阿尔茨海默病定向力加工与自动记忆巩固的功能磁共振研究及新量表的应用
(81661148045)国家自然科学基金 中以国际合作项目 201610-201909 166万
2.脑活动的低频振荡与持续注意之功能磁共振研究(31471084) 国家自然科学基金
面上项目 201501-201812 90万
3.静息态功能磁共振低频振幅的生理机制及其对异常脑活动的精准定位价值(81520108016)
国家自然科学基金 重点国际合作项目 201601-202012 235万
发表论文(节选论文)
Luo FF, Wang JB, Yuan LX, Zhou ZW, Xu H, Ma SH, Zang YF*, Zhang M*. Higher Sensitivity and Reproducibility of Wavelet-Based Amplitude of Resting-State fMRI. Front Neurosci. 2020 Mar 31;14:224. doi: 10.3389/fnins.2020.00224. eCollection 2020. PMID: 32300288
Wang J, Deng XP, Wu YY, Li XL, Feng ZJ, Wang HX, Jing Y, Zhao N, Zang YF*, Zhang J*. High-Frequency rTMS of the Motor Cortex Modulates Cerebellar and Widespread Activity as Revealed by SVM. Front Neurosci. 2020 Mar 19;14:186. doi: 10.3389/fnins.2020.00186. eCollection 2020. PMID: 32265624
Jing Y, Zhao N, Deng XP, Feng ZJ, Huang GF, Meng M, Zang YF*, Wang J*. Pregenual or subgenual anterior cingulate cortex as potential effective region for brain stimulation of depression. Brain Behav. 2020 Mar 8:e01591. doi: 10.1002/brb3.1591. [Epub ahead of print] PMID: 32147973
Wang B, Wang J, Cen Z, Wei W, Xie F, Chen Y, Sun H, Hu Y, Yang D, Lou Y, Chen X, Ouyang Z, Chen S, Wang H, Wang L, Wang S, Qiu X, Ding Y, Yin H, Wu S, Zhang B, Zang YF*, Luo W*. Altered Cerebello-Motor Network in Familial Cortical Myoclonic Tremor With Epilepsy Type 1. Mov Disord. 2020 Mar 4. doi: 10.1002/mds.28014. [Epub ahead of print]
Jiang K, Wang J, Zheng A, Li L, Yi Y, Ding L, Li H, Dong X*, Zang Y*. Amplitude of low-frequency fluctuation of resting-state fMRI in primary nocturnal enuresis and attention deficit hyperactivity disorder. Int J Dev Neurosci. 2020 Feb 24. doi: 10.1002/jdn.10020. [Epub ahead of print] PMID: 32092172
Jia XZ, Sun JW, Ji GJ, Liao W, Lv YT, Wang J, Wang Z, Zhang H, Liu DQ, Zang YF*. Percent amplitude of fluctuation: A simple measure for resting-state fMRI signal at single voxel level. PLoS One. 2020 Jan 8;15(1):e0227021. doi: 10.1371/journal.pone.0227021. eCollection 2020. PMID: 31914167
Wang J, Meng HJ, Ji GJ, Jing Y, Wang HX, Deng XP, Feng ZJ, Zhao N, Zang YF*, Zhang J*. Finger Tapping Task Activation vs. TMS Hotspot: Different Locations and Networks. Brain Topogr. 2020 Jan;33(1):123-134. doi: 10.1007/s10548-019-00741-9. Epub 2019 Nov 6.
Jia XZ, Wang J, Sun HY, Zhang H, Liao W, Wang Z, Yan CG, Song XW, Zang YF*. RESTplus: an improved toolkit for resting-state functional magnetic resonance imaging data processing. Sci Bull (Beijing) 2019 64(14), 953-4.
Yan CG*, Chen X, Li L, Castellanos FX, Bai TJ, Bo QJ, Cao J, Chen GM, Chen NX, Chen W, Cheng C, Cheng YQ, Cui XL, Duan J, Fang YR, Gong QY, Guo WB, Hou ZH, Hu L, Kuang L, Li F, Li KM, Li T, Liu YS, Liu ZN, Long YC, Luo QH, Meng HQ, Peng DH, Qiu HT, Qiu J, Shen YD, Shi YS, Wang CY, Wang F, Wang K, Wang L, Wang X, Wang Y, Wu XP, Wu XR, Xie CM, Xie GR, Xie HY, Xie P, Xu XF, Yang H, Yang J, Yao JS, Yao SQ, Yin YY, Yuan YG, Zhang AX, Zhang H, Zhang KR, Zhang L, Zhang ZJ, Zhou RB, Zhou YT, Zhu JJ, Zou CJ, Si TM, Zuo XN, Zhao JP*, Zang YF*. Reduced default mode network functional connectivity in patients with recurrent major depressive disorder. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9078-9083.
Yan C*, Zang Y*. DPARSF: a MATLAB toolbox for "pipeline" data analysis of resting-state fMRI. Front. Syst. Neurosci. 2010, 4:13. doi:10.3389/fnsys.2010.00013.
Zang YF, Jiang TZ, Lu YL, He Y, Tian LX, Regional Homogeneity Approach to fMRI Data Analysis. NeuroImage, 2004, 22:394-400.
Zang YF*, He Y, Zhu CZ, Cao QJ, Sui MQ, Liang M, Tian LX, Jiang TZ, Wang YF. Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev. 2007 Mar;29(2):83-91.
Song XW, Dong ZY, Long XY, Li SF, Zuo XN, Zhu CZ, He Y, Yan CG, Zang YF*. REST: a toolkit for resting-state functional magnetic resonance imaging data processing. PLoS ONE 6(9): e25031.
Zou QH, Zhu CZ, Yang Y, Zuo XN, Long XY, Cao QJ, Wang YF, Zang YF*. An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: Fractional ALFF. J Neurosci Methods. 2008 Jul 15;172(1):137-41.
Yan C, Liu D, He Y, Zou Q, Zhu C, Zuo X, Long X, Zang Y*. Spontaneous brain activity in the default mode network is sensitive to different resting-state conditions with limited cognitive load. PLoS ONE. 2009 May 29;4(5):e5743.
Cao Q, Zang Y*, Sun L, Sui M, Long X, Zou Q, Wang Y*. Abnormal neural activity in children with attention deficit hyperactivity disorder: a resting-state functional magnetic resonance imaging study. Neuroreport. 2006 Jul 17;17(10):1033-6.
Long XY, Zuo XN, Kiviniemi V, Yang Y, Zou QH, Zhu CZ, Jiang TZ, Yang H, Gong QY, Wang L, Li KC, Xie S, Zang YF*. Default mode network as revealed with multiple methods for resting-state functional MRI analysis. J Neurosci Methods. 2008 Jun 30;171(2):349-55.
Zang YF, Jin Z, Weng XC, Zhang L, Zeng YW, Yang L, Wang YF, Seidman LJ, Faraone SV. Functional MRI in Attention Deficit Hyperactivity Disorder: Evidence for Hypofrontality. Brain Dev. 2005 27:544-50.
Cao X, Cao Q, Long X, Sun L, Sui M, Zhu C, Zuo X, Zang Y*, Wang Y*. Abnormal resting-state functional connectivity patterns of the putamen in medication-naïve children with attention deficit hyperactivity disorder. Brain Res. 2009 Dec 15;1303:195-206.
Zou QH, Long XY, Zuo XN, Yan CG, Zhu CZ, Yang YH, Liu DQ, He Y*, Zang YF*. Functional connectivity between the thalamus and visual cortex under eyes closed and eyes open conditions: a resting-state fMRI study. Human Brain Mapping, 2009 Sep;30(9):3066-78.
Tian L, Ren J, Zang Y*. Regional homogeneity of resting state fMRI signals predicts Stop signal task performance. Neuroimage. 2012 Dec 10;60(1):539-544.
Han Y, Yang Y, Lv YT, Zhu CZ, He Y, Tang HH, Gong QY, Luo YJ, Zang YF*, Dong Q. Gray matter density and white matter integrity in pianist’s brain: a combined structural and diffusion tensor MRI study. Neurosci Lett. 2009 Jul 31;459(1):3-6. Epub 2008 Jul 24. (Plenary article)
Liu D, Yan C, Ren J, Yao L, Kiviniemi VJ, Zang Y*. Using coherence to measure regional homogeneity of resting-state fMRI signal. Front. Syst. Neurosci. 2010, 4:24.
An L, Cao QJ, Sui MQ, Sun L, Zou QH, Zang YF, Wang YF. Local synchronization and amplitude of the fluctuation of spontaneous brain activity in attention-deficit hyperactivity disorder: a resting-state fMRI study. Neurosci Bull. 2013 Oct;29(5):603-13.Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kötter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP. Toward discovery science of human brain function. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4734-9. (Zang YF is one of 8 steering members of this FCP1000 project.)
主持基金(节选):
1.阿尔茨海默病定向力加工与自动记忆巩固的功能磁共振研究及新量表的应用
(81661148045)国家自然科学基金 中以国际合作项目 201610-201909 166万
2.脑活动的低频振荡与持续注意之功能磁共振研究(31471084) 国家自然科学基金
面上项目 201501-201812 90万
3.静息态功能磁共振低频振幅的生理机制及其对异常脑活动的精准定位价值(81520108016)
国家自然科学基金 重点国际合作项目 201601-202012 235万
专利:
1. 臧玉峰、朱新乐. 一种确定脑病变投影位置的脑病变投影仪. 发明专利. (专利号:ZL 99 1 07729.6.)
2. 贺永、蒋田仔、臧玉峰、吕英立. 一种基于图论的脑区功能连接的检测方法. 发明专利. (专利号:200310120539)
3. 吕英立、蒋田仔、臧玉峰. 基于约束化的脑功能核磁共振时间序列分析方法. 发明专利. (专利号:200310120541)
4. 臧玉峰、蒋田仔、吕英立、贺永. 一种基于局部一致性的功能磁共振数据分析方法. 发明专利. (专利号:2003 1 0120625.3)
5. 蒋田仔、龚高浪、朱朝喆、臧玉峰. 基于尺度不变的扣带分析方法. 发明专利. (专利号:200410036821)
6. 臧玉峰、贺永、蒋田仔、朱朝喆. 功能磁共振数据处理中的功率谱定量分析方法. 发明专利. (专利号:200410101882)
7. 蒋田仔、田丽霞、梁 猛、臧玉峰、贺 永. 综合时域与空域信息分析功能磁共振数据的方法. 发明专利. (专利号:200510086959)
8. 静息态脑功能磁共振数据处理软件(REST, http://www.restfmri.net)(软著登字第092726号,著作权人:北京师范大学)
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