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吕亚婷

基本资料

吕亚婷,博士,副研究员

电子邮件:lvyating198247@gmail.com

研究方向

多模态磁共振方法在脑卒中预防、诊断、治疗中的应用:

1. 静息态功能磁共振方法(时间移位分析)用于脑缺血疾病的灌注损伤的无创检测

2. 多模态磁共振方法在脑卒中后运动障碍、情绪障碍中的应用

3. 重复经颅磁刺激(rTMS)治疗卒中后运动障碍的脑机制研究


个人履历

学习经历:

2009年07月——2013年09月 德国马克思普朗克人类认识与大脑科学研究所 Max Planck Institute for Human Cognitive and Brain Sciences, Cognitive Neurology 医学博士

2005年09月——2008年07月 中国科学院自动化研究所模式识别国家重点实验室 工学硕士

2000年09月——2005年07月 天津医科大学生物医学工程系 工学学士

工作经历:

2014年2月——至今 杭州师范大学 认知与脑疾病研究中心 副研究员

2008年07月——2009年07月 中国科学院自动化研究所模式识别国家重点实验室 研究助理

科学研究

科研项目:

科技部国家重点研发计划“重大慢性非传染性疾病防控研究 ”专项题目:《卒中后抑郁的多维度筛查防治技术开发与应用》,课题题目:《卒中后抑郁脑区及功能环路 MRI 变化特征》,2017YFC1310002,2017.7--2021.12 ,课题负责人

杭州师范大学省优势特色学科培育项目,中青年教师助推项目,重复经颅磁刺激对大脑运动功能影响的脑机制研究,20JYXK026,2021.1--2023.12,主持

浙江省卫生健康科技计划面上项目,2021KY249,急性缺血性脑卒中溶栓治疗后大脑灌注与功能的无创评估,2021.1--2023.12,主持

杭州市在杭创业创新项目:颅内血管支架成形术治疗前后大脑血流灌注的无创评估,2019-2021,主持

国家自然科学基金面上项目:短暂性脑缺血发作患者灌注损伤无创评估以及缺血发作后大脑结构、功能的改变:多模态磁共振成像研究,81771911,2018.1-2019.12,主持

国家自然科学青年基金项目:《静息态fMRI 方法在急性缺血性中风诊断中的应用研究》,81301210,2014.1--2016.12主持

科技部国家重点研发计划“重大慢性非传染性疾病防控研究 ”专项题目:《帕金森病(PD)的早期诊断新技术研发》,子课题题目:《结构和功能磁共振研究》,2016YFC1306503,2016.9--2021.6,3/14子课题合作单位负责人

国家自然科学基金面上项目:《多模式磁共振成像检测与识别轻度认知障碍和阿尔茨海默病的研究》,81471642, 2015.1--2017.12主要合作者参与,4/8

科研成果:

1. Lv Y, Wei W, Han X, Song Y, Han Y, Zhou C, Zhou D, Zhang F, Wu X, Liu J, Zhao L, Zhang C, Wang N, Wang J. Multiparametric and multilevel characterization of morphological alterations in patients with transient ischemic attack. Hum Brain Mapp. 2021 Jan 19. doi: 10.1002/hbm.25344. Epub ahead of print.

2. 朱婷婷. 吕亚婷*. 卒中后抑郁的多模态磁共振影像学研究进展[J]. 实用放射学杂志. 2020.12(36):144-147.

3. Wang X#, Li L#, Wei W, Zhu T, Huang GF, Li X, Ma HB, Lv Y*. Altered activation in sensorimotor network after applying rTMS over the primary motor cortex at different frequencies. Brain Behav. 2020 Jul;10(7):e01670. doi: 10.1002/brb3.1670

4. Jiang Z, Zhang X, Lv Y, Zheng X, Zhang H, Zhang X, Jiang C, Lin G*, Gu W*. Preoperative Altered Spontaneous Brain Activity and Functional Connectivity Were Independent Risk Factors for Delayed Neurocognitive Recovery in Older Adults Undergoing Noncardiac Surgery. Neural Plast. 2020 Jun 16;2020:9796419. doi: 10.1155/2020/9796419.

5. Yuan LX, Zhao N, Wang XQ, Lv YT and He H (2021) Echo Time Dependency of Local Activity Metrics of Resting-State Functional MRI. Front. Neurosci. 15:619412.doi: 10.3389/fnins.2021.619412

6. Wei W#, Zhu T#, Wang X, Li L, Zou Q, Lv Y*. Altered Topological Organization in the Sensorimotor Network After Application of Different Frequency rTMS. Front Neurosci. 2019 Dec 19; 13:1377. doi: 10.3389/fnins.2019.0137

7. Zhu T#, Li L#, Song Y, Han Y, Zhou C, Zhou D, Zhang F, Xue Q, Liu J, Zhao L, Zhang C, Lv Y*, Han X. Altered Functional Connectivity within Default Mode Network in Patients with Transient Ischemic Attack: A Resting-State Functional Magnetic Resonance Imaging Study. Cerebrovasc Dis. 2019 Nov;48(1-2):61-69. doi: 10.1159/000502884. Epub 2019 Sep 12.

8. Zhang X, Li H, Lv Y, Zhu Z, Shen X, Lu Q, Wang W, Wang Z, Jiang Z, Yang L, Lin G, Gu W. Premorbid Alterations of Spontaneous Brain Activity in Elderly Patients With Early Post-operative Cognitive Dysfunction: A Pilot Resting-State Functional MRI Study. Front Neurol. 2019 Oct 9;10:1062. doi: 10.3389/fneur.2019.01062. eCollection 2019.

9. Lv Y, Han X, Song Y, Han Y, Zhou C, Zhou D, Zhang F, Xue Q, Liu J, Zhao L, Zhang C, Li L, Wang J*. Toward neuroimaging-based network biomarkers for transient ischemic attack. Hum Brain Mapp. 2019 Aug 1;40(11):3347-3361. doi: 10.1002/hbm.24602. Epub 2019 Apr 19.

10. Jia XZ, Sun JW, Ji GJ, Liao W, Lv YT, Wang J, Wang Z, Zhang H, Liu DQ, Zang YF. Percent amplitude of fluctuation: A simple measure for resting-state fMRI signal at single voxel level. PLoS One. 2020 Jan 8;15(1):e0227021. doi: 10.1371/journal.pone.0227021.

11. Lv Y#*, Li L#, Song Y, Han Y, Zhou C, Zhou D, Zhang F, Xue Q, Liu J, Zhao L, Zhang C and Han X*. The Local Brain Abnormalities in Patients With Transient Ischemic Attack: A Resting-State fMRI Study. Front Neurosci. 2019 Jan 31;13:24. doi: 10.3389/fnins.2019.00024.

12. Lv Y, Wei W, Song Y, Han Y, Zhou C, Zhou D, Zhang F, Xue Q, Liu J, Zhao L, Zhang C, Li L, Zang YF, Han X*. Non-invasive evaluation of cerebral perfusion in patients with transient ischemic attack: an fMRI study. J Neurol. 2019 Jan;266(1):157-164. doi: 10.1007/s00415-018-9113-3.

13. Chen Q, Zhou J, Zhang H, Chen Y, Mao C, Chen X, Ni L, Zhuo Z, Zhang Y, Geng W, Yin X*, Lv Y*. One-step analysis of brain perfusion and function for acute stroke patients after reperfusion: A resting-state fMRI study. J Magn Reson Imaging. 2019 Jul;50(1):221-229. doi: 10.1002/jmri.26571. Epub 2018 Dec 19.

14. Ni L, Li J, Li W, Zhou F, Wang F, Schwarz CG, Liu R, Zhao H, Wu W, Zhang X, Li M, Yu H, Zhu B, Villringer A, Zang Y, Zhang B*, Lv Y*, Xu Y*. The value of resting-state functional MRI in subacute ischemic stroke: comparison with dynamic susceptibility contrast-enhanced perfusion MRI. Sci Rep. 2017 Jan 31, 7: 41586. doi: 10.1038/srep41586.

15. Lv Y, Margulies DS, Villringer A, Zang YF. Effects of finger tapping frequency on regional homogeneity of sensorimotor cortex. PLoS One, 2013, 8(5): e64115.

16. Lv Y, Margulies DS, Cameron Craddock R, Long X, Winter B, Gierhake D, Endres M, Villringer K, Fiebach J, Villringer A. Identifying the perfusion deficit in acute stroke with resting-state functional magnetic resonance imaging. Ann Neurol, 2013, 73(1): 136-140.

17. Lv YT, Yang H, Wang DY, Li SY, Han Y, Zhu CZ, He Y, Tang HH, Gong QY, Zang YF. Correlations in spontaneous activity and gray matter density between left and right sensorimotor areas of pianists. NeuroReport, 2008, 19(6): 631-634.

18. Han Y, Yang H, Lv YT, Zhu CZ, He Y, Tang HH, Gong QY, Luo YJ, Zang YF, Dong Q. Gray matter density and white matter integrity in pianists' brain: A combined structural and diffusion tensor MRI study. Neurosci Lett. 2009 Jul 31; 459(1): 3-6.

19. Cao Q, Sun L, Gong G, Lv Y, Cao X, Shuai L, Zhu C, Zang Y, Wang Y. The macrostructural and microstructural abnormalities of corpus callosum in children with attention deficit/hyperactivity disorder: a combined morphometric and diffusion tensor MRI study. Brain Res. 2010 Jan 15; 1310: 172-80.

20. Margulies DS, Böttger J, Long X, Lv Y, Kelly C, Schäfer A, Goldhahn D, Abbushi A, Milham MP, Lohmann G, Villringer A. Resting developments: a review of fMRI post-processing methodologies for spontaneous brain activity. MAGMA. 2010 Dec; 23(5-6): 289-307.

21. Li Y, Ding G, Booth JR, Huang R, Lv Y, Zang Y, He Y, Peng D. Sensitive period for white-matter connectivity of superior temporal cortex in deaf people. Hum Brain Mapp. 2012 Feb; 33(2): 349-59.

22. Li S, Han Y, Wang D, Yang H, Fan Y, Lv Y, Tang H, Gong Q, Zang Y, He Y. Mapping Surface Variability of the Central Sulcus in Musicians. Cereb Cortex. 2010 Jan; 20(1): 25-33.

23. Liu Z, Xu C, Xu Y, Wang Y, Zhao B, Lv Y, Cao X, Zhang K, Du C. Decreased regional homogeneity in insula and cerebellum: a resting-state fMRI study in patients with major depression and subjects at high risk for major depression. Psychiatry Res. 2010 Jun 30; 182(3): 211-5.

24. Li Q, Sun J, Guo L, Zang Y, Feng Z, Huang X, Yang H, Lv Y, Huang M, Gong Q. Increased fractional anisotropy in white matter of the right frontal region in children with attention-deficit/hyperactivity disorder: a diffusion tensor imaging study. Neuro Endocrinol Lett. 2010;31(6):747-53. doi: 10.1159/000287255.


所获专利

Arno Vilringer, Daniel S. Margulies,Yating Lv, Richard Cameron Craddock. Inventor of “Method and apparatus for visualization of tissue perfusion by means of assessing BOLD signal fluctuations”. European Patent Office.

 



【来源: 日期:2014-03-24 09:28:01 点击:4138

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