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车先伟

车先伟 硕士生导师 副研究员 杭州市第二人民医院双聘研究员

E-mailxianwei.che@hznu.edu.cnxwcheswu@gmail.com

研究方向

主要研究方向为应用EEG和同步TMS-EEG(及TMS-EMG)探索慢性疼痛的神经可塑性变化以及使用经颅磁刺激(Transcranial Magnetic StimulationTMS)缓解慢性疼痛。经颅磁刺激是一种安全、无创的神经调控方法。现有研究已经表明TMS在治疗慢性疼痛中有极大的潜力和临床价值 。与此同时,单脉冲TMS诱发的神经响应能够被头皮EEG电极记录到,同步TMS-EEG能够探测到人脑高级皮层的神经可塑性,克服了TMS-EMG只能测量运动皮层可塑性的局限。

个人履历

学习经历:

201509---201906月  神经科学博士, Monash University 2021 QS=55; 2021 USNEWS=48,导师:https://www.researchgate.net/profile/Paul-Fitzgerald-8

201209---201506月  心理学硕士,心理学部 西南大学

工作经历:

201911今   副研究员,杭州市第二人民医院双聘研究员, 杭州师范大学

科学研究

科研项目

1. 探索重复经颅磁刺激(rTMS)在慢性神经病理性疼痛中的持续镇痛效应及其神经可塑性机制(国家自然科学基金,2021-202324万)

2. 背外侧前额叶重复经颅磁刺激(rTMS)镇痛的时间动态性及与神经可塑性关系(杭州师范大学优势学科项目,2021-20228万)

发表论文*通讯作者)

*Che, X., Cash, R., Fitzgerald, P., &, Fitzgibbon B. Meta-analytic evidence on the analgesic effects of high-frequency rTMS over the dorsolateral prefrontal cortex. (under review in Brain Stimulation)

*Che, X., Cash, R., Fitzgerald, P., &, Fitzgibbon B. The dorsomedial prefrontal cortex as a flexible hub mediating behavioral as well as local and distributed neural effects of social support context on pain: A Theta Burst Stimulation and TMS-EEG study. NeuroImage. 2019, https://doi.org/10.1016/j.neuroimage.2019.116053 (2018 IF = 5.8)

Luo, X., Jian, Z., & *Che, X. Investigating the Influence and a Potential Mechanism of Self-compassion on Experimental Pain: Evidence from a Compassionate Self-talk Protocol and Heart Rate Variability. Journal of Pain (accepted on 18/11/2019) (2018 IF = 5.42). doi: 10.1016/j.jpain.2019.11.006

*Che, X., Cash, R., Chung, S., Fitzgerald, P., &, Fitzgibbon B. Investigating the influence of social support on experimental pain and related physiological arousal: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 2018; 92:437-452. (2018 IF = 8.01)

Luo, X., Qiao, L., & *Che, X., Self-compassion Modulates Heart Rate Variability and Negative Affect to Experimentally Induced Stress. Mindfulness, 9, 1522-1528. (2017 IF = 3.02)

*Che, X., Cash, R., Ng, S., Fitzgerald, P., & Fitzgibbon B. (2018). A Systematic Review of the Processes Underlying the Main and the Buffering Effect of Social Support on the Experience of Pain. Clinical Journal of Pain 34, 1061-1076. (2017 IF = 3.21)

*Che, X., Cash, R., Fitzgerald, P., &, Fitzgibbon B. (2017). The social regulation of pain: autonomic and neurophysiological changes associated with perceived threat. Journal of Pain, 19, 496-505. (2018 IF = 5.42)

Che, X., Luo, X., Tong, D., Fitzgibbon, B., & Yang, J. (2015). Habitual suppression relates to difficulty in regulating emotion with cognitive reappraisal. Biological Psychology, 112, 20-26. (2017 IF = 2.89)

Che, X., Wei, D., Li, W., Li, H., Qiao, L., Qiu, J., Zhang, Q., & Liu, Y. (2014). The correlation between gray matter volume and perceived social support: a voxel-based morphometry study. Social Neuroscience, 9, 152‐159. (2017 IF = 2.58)

Che, X., Zhao, J., Wei, D., Li, B., Guo, Y., Qiu, J., Zhang, Q., & Liu, Y. (2014). Synchronous activation within the default mode network correlates with perceived social support. Neuropsychologia, 63, 26-33. (2017 IF = 2.89)

社会工作

国际疼痛学会(IASP)会员

澳亚神经调控协会(ABSS)会员

担任Brain Stimulation, NeuroImage, Scientific Reports杂志审稿人

其他

荣誉奖励:

IASP Financial Aid for the 17th World Congress on Pain, Boston, USA(国际疼痛学会)

中国留学基金委海外攻读博士学位奖学金 (2015-2019)

培训交流:

BRAIN Conference 2021, online, 口头报告及海报张贴

17th World Congress on Pain, Boston, USA, 2018 海报张贴

Australasian Society for Social & Affective Neuroscience (AS4SAN), Melbourne, Australia, 2017 口头报告

Australian Pain Society, Sydney, Australia, 2017 海报张贴

21st annual meeting of the OHBM, Hawaii, USA 海报张贴

西南大学认知与人格教育部重点实验室2014 磁共振扫描员

学生指导

叶扬 2020级硕士 杭州师范大学

刘颖 2020级博士 浙江大学医学院附属第二医院 (联合导师)

欢迎对经颅磁刺激(TMS)、疼痛、神经调控及神经可塑性感兴趣的学生报考。更多信息请参见: https://www.researchgate.net/profile/Xianwei_Che


【来源: 日期:2020-05-06 14:41:36 点击:1102

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