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车先伟

车先伟 硕士生导师 副研究员 杭州市第二人民医院双聘研究员

E-mailxianwei.che@hznu.edu.cnxwcheswu@gmail.com

研究方向

2019年获世界百强名校莫纳什大学神经科学博士学位。现任杭州师范大学副研究员,杭州市第二人民医院双聘PI。主要研究方向为应用经颅磁刺激(TMS)缓解慢性疼痛以及使用同步TMS-EEG,TMS-EMG和EEG技术探索慢性疼痛的神经可塑性变化。主持国家自然科学基金项目(2021-2023),作为子课题负责人主持浙江省重点研发计划攻关项目(2022-2024)。以第一或通讯作者在Brain Stimulation, Neuroscience & Biobehavioral Reviews, NeuroImage, Cerebral Cortex等神经科学高影响杂志发表文章多篇。2021年获杭州市高层次人才特殊支持计划培养类人才以及杭师大附属医院科研创新奖。目前指导硕士研究生4名,博士研究生1名。

个人履历

学习经历:

201509---201906 神经科学博士, Monash University (2021 QS=55; 2021 USNEWS=48,导师:https://www.researchgate.net/profile/Paul-Fitzgerald-8

201209---201506 心理学硕士,心理学部 西南大学

工作经历:

201911 副研究员,杭州师范大学

202005 双聘PI 杭州市第二人民医院

科学研究

科研项目

1. 探索重复经颅磁刺激(rTMS)在慢性神经病理性疼痛中的持续镇痛效应及其神经可塑性机制(国家自然科学基金,2021-2023,主持,24万)

2. 面向脑机接口的外部信息输入与神经调控技术研究(浙江省‘尖兵’重点研发攻关计划,2022-2024,子课题负责人,负责经费20/总185万)

3. 神经药理学联合神经可塑性方法探索rTMS镇痛神经机制(杭州市生物医药和健康产业发展扶持科技专项,2022-2023,主持,8万)

4. 背外侧前额叶重复经颅磁刺激(rTMS)镇痛的时间动态性及与神经可塑性关系(杭州师范大学优势学科项目,2021-2022,主持,8万)

发表论文((* 通讯作者,更多文章请参见https://www.researchgate.net/profile/Xianwei_Che

*Xianwei Che, Robin F.H. Cash, Xi Luo, Hong Luo, Xiaodong Lu, Feng Xu,

Yu-Feng Zang, Paul B. Fitzgerald, Bernadette M. Fitzgibbon. High-frequency rTMS over the dorsolateral prefrontal cortex on chronic and provoked pain: A systematic review and meta-analysis. Brain Stimulation, 2021, 14:1135-1146 (2021 IF = 8.9, 中科院医学一区,通讯作者).

*Che, X., Fitzgibbon B., Yang, Y., Wang, J., Luo, H., Fitzgerald, P., &, Cash, R. Characterising the Optimal Pulse Number and Frequency for Inducing Analgesic Effects with Motor Cortex rTMS. Brain Stimulation, 2021, 14:1081-1083 (2021 IF = 8.9, 中科院医学一区,通讯作者).

*Che, X., Cash, R., Chung, S., Fitzgerald, P., &, Fitzgibbon B. Investigating the influence of social support on experimental pain and related physiological arousal: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 2018; 92:437-452. (2018 IF = 8.0, 中科院医学一区,通讯作者)

*Che, X., Cash, R., Fitzgerald, P., &, Fitzgibbon B. The dorsomedial prefrontal cortex as a flexible hub mediating behavioral as well as local and distributed neural effects of social support context on pain: A Theta Burst Stimulation and TMS-EEG study. NeuroImage 2019; e116053. (2019 IF = 5.9, 中科院医学一区,通讯作者)

Ye Y, Wang J, Che X*. Concurrent TMS-EEG to Reveal the Neuroplastic Changes in the Prefrontal and Insular Cortices in the Analgesic Effects of DLPFC-rTMS. Cerebral Cortex (accepted on 2021/11/23, 中科院医学一区,通讯作者).

J Li, K Xu, Y Guo, X Chen, G Li, L Qi, X *Che. Case evidence of repetitive transcranial magnetic stimulation in the management of refractory irritable bowel syndrome with comorbid depression. Brain Stimulation, 2022, 15:434-436 (2021 IF = 8.9, 中科院医学一区,通讯作者).

Luo, X., Jian, Z., & *Che, X. Investigating the Influence and a Potential Mechanism of Self-compassion on Experimental Pain: Evidence from a Compassionate Self-talk Protocol and Heart Rate Variability. Journal of Pain 2020; 7:790-797. (2018 IF = 5.42中科院医学二区,通讯作者).

*Che, X., Cash, R., Fitzgerald, P., &, Fitzgibbon B. (2018). The social regulation of pain: autonomic and neurophysiological changes associated with perceived threat. Journal of Pain, 19, 496-505. (2018 IF = 5.42中科院医学二区,通讯作者)

X Che*, X Luo, Y Chen, B Li, X Li, X Li, L Qiao. Social touch modulates pain-evoked increases in facial temperature. Current Psychology, 2021,1-10. (JCR心理学一区,通讯作者)

X Che, X Luo, D Tong, BM Fitzgibbon, J Yang. Habitual suppression relates to difficulty in regulating emotion with cognitive reappraisal. 2015, Biological psychology 112, 20-26. (JCR实验心理学一区)

X Che, Q Zhang, J Zhao, D Wei, B Li, Y Guo, J Qiu, Y Liu. Synchronous activation within the default mode network correlates with perceived social support. 2014, Neuropsychologia 63, 26-33. (JCR行为科学一区)

X Luo, L Qiao, X Che*. Self-compassion modulates heart rate variability and negative affect to experimentally induced stress. 2018, Mindfulness 9 (5), 1522-1528. (JCR临床心理学一区,通讯作者)

Ying Liu, Lina Yu, Xianwei Che*, Min Yan*. Prolonged Continuous Theta Burst Stimulation to Demonstrate a Larger Analgesia as well as Cortical Excitability Changes Dependent on the Context of a Pain Episode. 2021. Accepted: 09 Dec 2021. https://www.frontiersin.org/articles/10.3389/fnagi.2021.804362/abstract (中科院医学二区,共同通讯作者)

社会工作

国际疼痛学会(IASP)会员

澳亚神经调控协会(ABSS)会员

担任Brain Stimulation, NeuroImage, Scientific Reports等杂志审稿人

International Journal of Environmental Research and Public Health 客座编辑

国际脑科学前言杂志 编委

其他

荣誉奖励:

·杭州市高层次人才特殊支持计划培养类人才(2021年,第一层次)

·IASP Financial Aid for the 17th World Congress on Pain, Boston, USA(国际疼痛学会)

·中国留学基金委海外攻读博士学位奖学金 (2015-2019)

培训交流:

BRAIN Conference 2021, online, 口头报告及海报张贴

17th World Congress on Pain, Boston, USA, 2018 海报张贴

Australasian Society for Social & Affective Neuroscience (AS4SAN), Melbourne, Australia, 2017 口头报告

Australian Pain Society, Sydney, Australia, 2017 海报张贴

21st annual meeting of the OHBM, Hawaii, USA 海报张贴

学生指导

王滢 谭柏林 师淑焱 2021级硕士 杭州师范大学

叶扬 2020级硕士 杭州师范大学

刘颖 2020级博士 浙江大学医学院附属第二医院 (联合导师)

欢迎对经颅磁刺激(TMS)、疼痛、神经调控及神经可塑性感兴趣的学生报考。更多信息请参见: https://www.researchgate.net/profile/Xianwei_Che

 


【来源: 日期:2020-05-06 14:41:36 点击:2255

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